Cardiovascular Biology

Research projects focus on angiogenesis and aim to identify the mechanisms by which endothelial cells interact and communicate with other cell types in the cardiovascular system. Of particular interest is the crosstalk between cardiac endothelial and cardiomyocytes. Thanks to established collaborations with several clinical institutions, this laboratory is particularly dedicated to the use of cellular and animal models of human disease, as well as viral and non-viral gene transfer approaches, for tissue revascularization. The ultimate goal is to develop new therapeutic approaches for and cancer treatment. His second interest in this group is in the field of laser light. His main interest is to understand how light interacts with cells and tissues and to use light to develop innovative therapeutic possibilities. A pivotal recent study in which the group participated demonstrated therapeutic efficacy of monoclonal antibodies targeting bone morphogenetic proteins (BMPs) after myocardial infarction. This study demonstrated that this antibody promotes cardiomyocyte survival after ischemic stroke while regulating fibrotic remodeling, leading to more elastic scar formation and improved cardiac function blood vessels and lymph vessels. The circulatory system plays a key role in the immune response and transport of nutrients and hormones, while the processes of angiogenesis and thrombosis (coagulation) are critical to system growth and maintenance. Some of the most important diseases of the cardiovascular system include atherosclerosis, coronary artery disease, stroke and hypertension. Diseases such as diabetes, obesity, dyslipidemia, cancer, fibrosis, and sepsis are primarily disorders of other systems, but their presence significantly increases the risk and incidence of cardiovascular disease. The Cardiovascular Biology in MD program falls under the broad heading of cardiovascular research with a focus on vascular biology. Majored in cardiovascular biology, smooth muscle gene regulation and differentiation, smooth muscle and cardiac muscle molecular biology, smooth muscle and endothelial cell receptor function and signaling, matrix and adhesion molecules in endothelial cell function, -cell communication , vascular development and inflammation, angiogenesis and remodeling. Training includes didactic courses, journal clubs, seminar series, and a unique interdisciplinary combination of extensive research experience. The interdisciplinary structure greatly increases training flexibility. Each student's training is tailored to their individual needs. The cardiovascular system includes the heart and blood vessels, which carry nutrients and oxygen to the body's tissues and remove carbon dioxide and other waste products from the body's tissues. The cardiovascular system includes pulmonary, systemic, and coronary circulation. The pulmonary circulation is the part of the cardiovascular system that carries oxygen-poor blood from the heart to the lungs and oxygen-rich blood back to the heart. Systemic circulation is the part of the cardiovascular system that carries oxygen-rich blood from the heart to the rest of the body and deoxygenated blood back to the heart. Coronary circulation is another part of the cardiovascular system that refers to the movement of blood through the tissues of the heart. Coronary arteries refer to the vessels that supply oxygenated blood to the heart muscle, and coronary veins refer to the vessels that remove deoxygenated blood from the heart muscle.

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Desrina R 
Managing Editor
International Journal of Pharmaceutical, Chemical and Biological Sciences